New eye scan method could unlock secrets of blurry vision disease
NCT ID NCT07347119
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will use a special type of eye scan (ultra-widefield OCTA) to measure blood vessel patterns in people with central serous chorioretinopathy (CSC), a condition that causes fluid buildup and blurry vision. Researchers aim to create a more precise way to analyze these images, moving beyond simple visual inspection. The study involves 120 adults with CSC who have not yet received treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study subjects were recruited from outpatients of the Medical Retina Department at Zhongshan Ophthalmic Center, and eligible cases meeting the study criteria were selected from the outpatient medical record system.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 to 60 years, inclusive; * Clinical diagnosis of central serous chorioretinopathy (CSC); * Completion of fundus fluorescein angiography (FFA) and indocyanine green angiography (ICGA) examinations; * Completion of ultra-widefield optical coherence tomography angiography (UWF-OCTA) imaging; * No prior history of pharmacological or surgical treatment for CSC; * Ability and willingness to provide written informed consent. Exclusion Criteria: -Presence of other ophthalmic diseases that may affect retinal or choroidal imaging or analysis, including but not limited to: Significant refractive media opacities interfering with OCTA imaging (e.g., severe cataract, vitreous hemorrhage); * Presence of systemic diseases that may affect study outcomes or participant safety; * Pregnant or lactating women; * History of psychiatric or mental disorders that may impair compliance; * Hemorrhagic diathesis or requirement for long-term anticoagulant therapy; * History of long-term systemic medication use that may affect choroidal or retinal circulation; * Presence of severe and/or uncontrolled comorbid medical conditions, including but not limited to: Uncontrolled diabetes mellitus; Uncontrolled hypertension; Active uncontrolled infection; Chronic obstructive pulmonary disease (COPD) with dyspnea at rest; * History of intraocular surgery or intravitreal injection within the past 6 months; * High refractive error defined as: Spherical equivalent (SE) \< -6.0 diopters or \> +3.0 diopters, or Axial length (AL) \> 26.0 mm; -Any other condition that, in the opinion of the investigator, would make participation unsafe or interfere with protocol adherence.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Zhongshan Ophthalmic Center, Sun Yat-sen University
Guangzhou, Guangdong, 510060, China
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Other studies related to the condition(s) this trial covers.