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New drug may ease painful erections in sickle cell patients

NCT ID NCT03938454

First seen Jan 22, 2026 · Last updated May 24, 2026 · Updated 21 times

Summary

This study tested a drug called crizanlizumab in 36 men with sickle cell disease who experience frequent, painful erections (priapism). The goal was to see if the drug could reduce the number of these episodes over 26 weeks. Participants reported their erections using an electronic system, and the study measured the change from before treatment to after.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Brody School of Medicine

    Greenville, North Carolina, 27834, United States

  • Childrens Hosp Boston Dept of Hematology

    Boston, Massachusetts, 02115, United States

  • Childrens National Hospital

    Washington D.C., District of Columbia, 20010, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Emory University School of Medicine

    Atlanta, Georgia, 30303, United States

  • Foundation for Sickle Cell Disease Research

    Hollywood, Florida, 33021, United States

  • LSU Medical Center

    Shreveport, Louisiana, 71130, United States

  • Montefiore Medical Center

    The Bronx, New York, 10461, United States

  • Prisma Health Upstate

    Greenville, South Carolina, 29615, United States

  • University Of Alabama

    Birmingham, Alabama, 35294, United States

  • University of Connecticut Health Center

    Farmington, Connecticut, 06030, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15213-2548, United States

  • University of Texas Medical School

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.