New study tests safer eczema treatment for pakistani patients
NCT ID NCT07437534
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two steroid-free ointments—crisaborole and tacrolimus—for treating mild-to-moderate eczema in 148 Pakistani patients aged 2 and older. Researchers will measure skin improvement and side effects over 8 weeks to see which works better and is safer. The goal is to provide local evidence for better eczema care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- crisaborole 2% ointment and tacrolimus 0.1% ointment
- What this could lead to
- If successful, this could help doctors choose safer, more effective eczema treatments for Pakistani patients, especially children.
- What could go wrong
- This is a small, early-phase study in one country, so results may not apply elsewhere. Both drugs have known side effects like burning or cancer risk.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 148 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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2 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: \* Patients aged ≥2 years of either gender. Diagnosed with mild to moderate atopic dermatitis based on Hanifin and Rajka criteria. SCORAD score between 15 and 40. Willing to participate and provide informed consent (from guardian for minors). Exclusion Criteria: \- Exclusion Criteria: \* Severe atopic dermatitis (SCORAD \> 40). History of hypersensitivity to tacrolimus or crisaborole. Use of systemic immunosuppressive therapy within the past 4 weeks. Presence of secondary bacterial or viral skin infection. Pregnant or lactating females. \-
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hayatabad Medical Complex
Peshawar, KPK, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a daily liquid medicine calm severe eczema in toddlers and preschoolers?
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- Can a Lab-Made antibody calm severe eczema?
- Is your nose fueling infected eczema and scabies sores?
- Can an eczema drug reshape the Skin's microbial community?