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Can a creatine boost help menopausal women? new study tests adherence

NCT ID NCT07580846

Symptom relief Sponsor: Margan Biotech Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tracks 100 women aged 40 and older with low estrogen (due to menopause or surgery) to see how well they follow a 12-week creatine supplement routine. Researchers will measure adherence, satisfaction, and any changes in muscle strength, body composition, quality of life, joint pain, and skin health. The goal is to understand if this supplement is easy to stick with and might ease menopause-related symptoms.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2026

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Estrogen-depleted adult women (menopause or late perimenopause) attending routine clinical practice consultations in participating centers and initiating nutritional supplementation.

Ages

40 to 75 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Biological female sex. * Age ≥40 years. * Estrogen-depleted status, defined as at least one of the following: natural menopause, defined as amenorrhea for ≥12 consecutive months; surgically induced menopause; late perimenopause with elevated FSH according to clinical judgment. * Absence of major comorbidities that would contraindicate use of the nutritional supplement or the recommended physical activity. * No relevant changes in usual treatment during the previous 3 months. * Ability to understand the study information and provide written informed consent. * Willingness to take the nutritional supplement according to the study instructions. * Willingness to follow general physical activity recommendations provided by the investigator. * Willingness and ability to attend the planned visits and complete study assessments through Week 12. Exclusion Criteria: * Initiation or modification of treatment with GLP-1 receptor agonists within the previous 12 weeks. * Presence of musculoskeletal or joint conditions that significantly limit the ability to perform regular physical activity or study-related functional assessments. * Clinically relevant renal or hepatic disease. * Current use of diuretics or potentially nephrotoxic medications. * Known allergy or intolerance to any component of the nutritional supplement. * Participation in another clinical study (nutritional, pharmacological, or interventional) within the previous 3 months. * Any medical condition or social circumstance that, in the investigator's judgment, could interfere with study participation, adherence, or data validity.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Estrogen deficiency Menopause

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    4 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Clinica Palacios Málaga

    NOT_YET_RECRUITING

    Málaga, Málaga, 29016, Spain

  • Clínica Palacios

    RECRUITING

    Madrid, Madrid, 28034, Spain

  • Ginegetafe

    RECRUITING

    Madrid, Madrid, 28901, Spain

  • Menoclinica by Palacios

    RECRUITING

    Madrid, Madrid, 28034, Spain

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