Creatine for a stronger voice in seniors? small study tests the idea
NCT ID NCT05856916
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether taking creatine supplements daily for 10 weeks can improve voice quality in people aged 65 and older who have age-related voice changes (presbyphonia). Twenty participants will be randomly assigned to receive either creatine or a placebo. Researchers will measure changes in voice handicap, vocal cord movement, and airflow to see if the supplement makes a difference.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- creatine monohydrate (a dietary supplement)
- What this could lead to
- If it works, this could point toward a simple, safe supplement to help older adults maintain a stronger, clearer voice.
- What could go wrong
- This is a very small, early-stage trial with only 20 participants. The study is currently suspended, so results may be delayed or never come. Creatine is generally safe, but benefits for voice are unproven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
May 2026
An estimate. Start dates often move.
- Expected to finish
-
Sep 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
65 to 100 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age 65 years or older 2. Desiring to participate in voice therapy Exclusion Criteria: 1. Lesions or abnormalities of the larynx not attributable to normal aging 2. Pre-existing renal disease 3. Pre-existing liver disease 4. Congestive heart failure 5. Blood urea nitrogen (BUN), creatine, alanine transaminase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), gamma-glutamyl transpeptidase (GGT) over reference range in the last 6 months 6. Concurrent medication associated with reduced renal clearance (e.g. Nonsteroidal Anti-inflammatory Drugs (NSAIDs), metformin) 7. History of prior vocal fold augmentation procedures 8. Cognitive disability 9. Unwillingness to participate in voice therapy
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Presbyphonia are added.
Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
NYU Langone Health
New York, New York, 10016, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.