Creatine and exercise during dialysis: a new hope for kidney patients?
NCT ID NCT07666815
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether taking creatine supplements and doing light exercise during dialysis sessions can help people with advanced kidney disease maintain muscle strength and body health. About 48 adults on dialysis will take either creatine or a placebo daily for 8 weeks, while also following an exercise program. The goal is to see if these simple additions can improve grip strength and other measures of physical function.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- creatine monohydrate
- What this could lead to
- If it works, this could point toward a simple way to help dialysis patients maintain muscle strength and physical function.
- What could go wrong
- This is a small, early-phase trial with only 48 participants over 8 weeks. The benefits may be modest or not last long, and creatine might not work well in this specific patient group.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1/2
Runs two stages together: safety and dose first, then whether the treatment works.
- Participants
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About 48 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * atients who are treated at the State Haemodialysis Centre. * Patients who receive haemodialysis three times a week. * Signature of informed consent. * Patients over 18 years of age, both men and women. * Patients who have been on haemodialysis for no more than two years. Exclusion Criteria: Patients who have had a limb amputated. * Patients who are in a state of anuria. * Inability to perform muscular resistance or aerobic resistance exercises. * Patients unable to perform physical exercise. * HIV-positive patients. Elimination. * Patients who voluntarily withdraw from the project. * Inability to perform physical exercise. * Death. * Adverse events related to creatine consumption.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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IMSS-Bienestar State Haemodialysis Centre
RECRUITINGColima, Coliima, 28048, Mexico
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Other studies related to the condition(s) this trial covers.
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- Smart insulin pump could ease diabetes management for kidney patients on dialysis