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New drug combo targets tough leukemia in early trial

NCT ID NCT04493164

First seen Nov 21, 2025 · Last updated Apr 29, 2026 · Updated 17 times

Summary

This study tests whether combining two drugs, CPX-351 and ivosidenib, can better control acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS) in people with a specific IDH1 gene mutation. About 30 adults who are either newly diagnosed or whose cancer has returned will receive the treatment. The goal is to see how many patients achieve remission and to check the safety of the combination.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.