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818 COVID-19 patients studied to uncover risk factors for severe disease

NCT ID NCT04887142

Knowledge-focused Sponsor: Zeljko Mijailovic Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study enrolled 818 adults hospitalized with COVID-19 to examine how genetic, inflammatory, and other blood markers relate to disease severity and death. Researchers tracked outcomes like recovery or death and analyzed risk factors using statistical models. The goal was to better understand why some patients become severely ill, which could improve future care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could help doctors better predict which COVID-19 patients are at highest risk of severe illness or death, potentially guiding more personalized care.
What could go wrong
This is an observational study, not a treatment trial, so it cannot prove cause and effect. The findings may not apply to all populations or future virus variants.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

818 people

The number who actually took part.

Started

Apr 2020

Finished

Feb 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients of both sexes with different socio-demographic and clinical characteristics, who were hospitalized due to COVID-19. The decision on hospitalization and further treatment of patients is at the discretion of the attending physicians. All participants will be prospectively followed during their hospital stay. Patients will be included in the study if they are at least 18 years old and if they give voluntary written consent to participate. Pregnant and breastfeeding women, patients transferred from other hospitals and those who die during the first 24 hours of hospitalization will be excluded. In this study, stratification of participants according to age to those older than 65 years and younger is provided only for the purposes of statistical data processing and analyse.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult age, 18 years old or more * Male or female * Hospitalization for COVID-19 after confirmation by SARS-CoV-2 rapid antigen test or RT-PCR * Voluntary written consent of the subject to participate Exclusion Criteria: * Pregnant and breastfeeding women * Fatal outcome during the first 24 hours of hospitalization * Inability to collect the necessary study data * Declining of the subject to voluntary participate in the study

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Conditions

The condition(s) this trial relates to.

COVID-19

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COVID -19

Contacts and locations

Locations

  • Faculty of Medical Sciences, University Clinical Center Kragujevac

    Kragujevac, Srbija, 34000, Serbia

  • General Hospital "Prim. dr. Abdulah Nakaš"

    Sarajevo, Bosnia and Herzegovina

  • KBC Rijeka, University of Rijeka

    Rijeka, Croatia

  • Spitali Amerikan

    Tirana, Albania

  • University of Montenegro, Faculty of Medicine

    Podgorica, Montenegro

More trials for these conditions

Other studies related to the condition(s) this trial covers.