Massive COVID-19 biobank aims to unlock secrets of severe disease
NCT ID NCT04318366
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is collecting medical information and biological samples from up to 6,000 people with COVID-19. Researchers want to find out which factors predict severe illness, death, or response to treatment. The goal is to better understand the disease and help guide future care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 6,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2020
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
COVID-19 patients
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients admitted to hospital with biological samples positive for SARS-CoV-2 * Patients admitted to hospital with negative test but clinical and radiological characteristics highly suggestive of SARS-CoV-2 disease * Patients discharged from emergency department with biological samples positive for SARS-CoV-2 Exclusion Criteria: * None
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
13 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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AIDS Immunopathogenesis Unit - IRCCS San Raffaele Scientific Institute
RECRUITINGMilan, Lombardy, 20132, Italy
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Autoimmunity and Vascular Inflammation Unit, Division of Regenerative Medicine, Stem Cells and Gene Therapy - IRCCS San Raffaele Scientific Institute
RECRUITINGMilan, Lombardy, 2012, Italy
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Department of Infection Diseases - IRCCS San Raffaele Scientific Institute -
RECRUITINGMilan, Lombardy, 20132, Italy
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Department of Internal Medicine - IRCCS San Raffaele Scientific Institute
RECRUITINGMilan, Lombardy, 20132, Italy
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Diabetes Research Institute -IRCCS San Raffaele Scientific Istitute
RECRUITINGMilan, Lombardy, 20132, Italy
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Division of Immunology, Transplantation and Infectious Diseases - IRCCS San Raffaele Scientific Institute
RECRUITINGMilan, Lombardy, 20132, Italy
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Division of Research of Regenerative Medicine, Cell and Gene Therapy - IRCCS San Raffaele Scientific Istitute
RECRUITINGMilan, Lombardy, 20132, Italy
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Laboratory of Microbiology and Virology - IRCCS San Raffaele Scientific Institute
RECRUITINGMilan, Lombardy, 20132, Italy
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Nephrology Unit - IRCCS San Raffaele Scientific Institute
RECRUITINGMilan, Lombardy, 20132, Italy
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Strategic Program in Nephrology and Dialysis - IRCCS San Raffaele Scientific Institute
RECRUITINGMilan, Lombardy, 20132, Italy
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Unit of Immunology, Rheumatology, Allergy and Rare Diseases - IRCCS San Raffaele Scientific Institute
RECRUITINGMilan, Lombardy, 2132, Italy
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Università Vita-Salute San Raffaele
RECRUITINGMilan, Mi, 20132, Italy
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Viral pathogens and biosafety Unit - IRCCS San Raffaele Scietific Institute
RECRUITINGMilan, Lombardy, 20132, Italy
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Other studies related to the condition(s) this trial covers.
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- Can lung ultrasound reveal COVID-19's signature in the lungs?
- When the immune system Can't fight back: tracking three respiratory viruses
- The household maze: how does COVID-19 move between family members?
- Can an oral drug stop COVID-19 from turning deadly?
- Can COVID-19 rapid tests slip into HIV and TB clinics without disrupting care?