CoQ10 showdown: which supplement boosts your cells best?
NCT ID NCT06640465
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed trial tested four different CoQ10 supplements (ubiquinol, ubiquinone, geranylgeraniol, and a combo) against a placebo in 150 healthy adults aged 40 and older. The goal was to see which supplement safely increases CoQ10 levels in the blood and improves self-reported health over 8 weeks. The study also checked blood markers like cholesterol and liver function.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- CoQ10 supplements (ubiquinol, ubiquinone, geranylgeraniol)
- What this could lead to
- If successful, this could show which CoQ10 supplement best boosts CoQ10 levels, possibly guiding healthier aging choices.
- What could go wrong
- This is a small, early-phase trial in healthy people, so results may not apply to those with medical conditions. Supplements may not improve actual health outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 2/3
Runs two stages together: whether the treatment works, then large-scale confirmation.
- Participants
-
150 people
The number who actually took part.
- Started
-
Oct 2024
- Finished
-
Sep 2025
- Lead sponsor
-
A research network
The lead sponsor is a research network or cooperative group.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
40 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Adult males or females age ≥ 40 years 2. Ability to read and speak English Exclusion Criteria: 1. Daily use within the past 2 months of any dietary supplements containing CoQ10 or geranylgeraniol (GG) 2. Taking a statin medication within the past 6 months 3. Current daily usage of H2 blockers or PPI medications 4. Current daily use of bisphosphonates 5. Current daily tobacco smoker 6. Known allergies to any substance in the study products 7. Currently pregnant or lactating women or women planning to become pregnant in the next 12 weeks 8. Current diagnosis of a chronic health condition (e.g., cancer, Crohn's disease) deemed clinically contraindicated for the study protocol. 9. Participant in a clinical trial in the previous 30 days. 10. Participants unable to provide consent
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CTMD Research
Palm Springs, Florida, 33046, United States
-
Cornerstone Health Community
Centennial, Colorado, 80111, United States
-
Functional Medicine of Idaho
Eagle, Idaho, 83616, United States
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New Dawn Wellness and Medical Center
Houston, Texas, 77082, United States
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True Health Center for Precision Medicine
El Dorado Hills, California, 95762, United States
-
Vida Integrated Health
Seattle, Washington, 98122, United States
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