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Two-Drug combo shows promise for aggressive blood cancer

NCT ID NCT03884998

First seen Jan 05, 2026 · Last updated May 23, 2026 · Updated 22 times

Summary

This early-phase study tests a combination of two drugs, copanlisib and nivolumab, in people with certain types of blood cancer that have changed into a more aggressive form (Richter's transformation or transformed non-Hodgkin lymphoma). The goal is to find the best dose and see if the combination is safe and can shrink tumors. About 27 adults will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • OHSU Knight Cancer Institute

    Portland, Oregon, 97239, United States

Conditions

Explore the condition pages connected to this study.