200,000 volunteers needed to unlock Cancer's secrets
NCT ID NCT04609072
First seen Jun 27, 2026 · Last updated Sep 18, 2026 · Updated 11 times
Summary
This long-term study aims to uncover the causes of cancer by following 200,000 adults aged 30–70 who have never had cancer. Participants complete online surveys, donate blood, urine, and saliva every few years, and share their electronic health records. The goal is to learn how lifestyle, genetics, and medical history influence cancer risk and find new ways to prevent it.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 200,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2021
- Expected to finish
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Dec 2070
An estimate. End dates often move.
- Lead sponsor
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A government research agency
The lead sponsor is the US National Institutes of Health.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients or members of participating health care organizations around the U.S.
- Ages
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30 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
* INCLUSION CRITERIA: Due to the minimal risk nature of this protocol, all individuals interested and able to participate in Connect for Cancer Prevention, who meet the eligibility criteria at time of initial study invitation, will be able to participate. In order to be eligible to participate in this study, an individual must meet all of the following criteria: * Patients or members of participating IHCS at the time of enrollment * Age between 30 and 70 years old at study invitation If an individual is determined to be ineligible at the time of enrollment due to age, the individual will be allowed to re-enroll at a later time once the recruit meets the age requirement. This includes recruits that did not meet the original age requirement of 40-65 years of age but now meet the updated age range of 30-70. EXCLUSION CRITERIA: An individual who meets any of the following criteria at time of initial study invitation will be excluded from participation in this study: * Individuals with a confirmed history of invasive cancer (other than non-melanoma skin cancer) * Individuals with known cognitive impairment documented in their medical record
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
9 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Baylor Scott and White Health
RECRUITINGDallas, Texas, 75246, United States
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HealthPartners
RECRUITINGMinneapolis, Minnesota, 55425, United States
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Henry Ford Health Systems
RECRUITINGDetroit, Michigan, 48202, United States
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Kaiser Permanente Colorado
RECRUITINGDenver, Colorado, 80247, United States
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Kaiser Permanente Georgia
RECRUITINGAtlanta, Georgia, 30305, United States
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Kaiser Permanente Hawaii
RECRUITINGHonolulu, Hawaii, 96814, United States
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Kaiser Permanente Northwest
RECRUITINGPortland, Oregon, 97086, United States
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Marshfield Clinic Health System
RECRUITINGMarshfield, Wisconsin, 54449, United States
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Sanford Health
RECRUITINGSioux Falls, South Dakota, 57117, United States
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University of Chicago Medical Center
ACTIVE_NOT_RECRUITINGChicago, Illinois, 60603, United States
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Other studies related to the condition(s) this trial covers.
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