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200,000 volunteers needed to unlock Cancer's secrets

NCT ID NCT04609072

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 18, 2026 · Updated 11 times

Summary

This long-term study aims to uncover the causes of cancer by following 200,000 adults aged 30–70 who have never had cancer. Participants complete online surveys, donate blood, urine, and saliva every few years, and share their electronic health records. The goal is to learn how lifestyle, genetics, and medical history influence cancer risk and find new ways to prevent it.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 200,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2021

Expected to finish

Dec 2070

An estimate. End dates often move.

Lead sponsor

A government research agency

The lead sponsor is the US National Institutes of Health.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients or members of participating health care organizations around the U.S.

Ages

30 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

* INCLUSION CRITERIA: Due to the minimal risk nature of this protocol, all individuals interested and able to participate in Connect for Cancer Prevention, who meet the eligibility criteria at time of initial study invitation, will be able to participate. In order to be eligible to participate in this study, an individual must meet all of the following criteria: * Patients or members of participating IHCS at the time of enrollment * Age between 30 and 70 years old at study invitation If an individual is determined to be ineligible at the time of enrollment due to age, the individual will be allowed to re-enroll at a later time once the recruit meets the age requirement. This includes recruits that did not meet the original age requirement of 40-65 years of age but now meet the updated age range of 30-70. EXCLUSION CRITERIA: An individual who meets any of the following criteria at time of initial study invitation will be excluded from participation in this study: * Individuals with a confirmed history of invasive cancer (other than non-melanoma skin cancer) * Individuals with known cognitive impairment documented in their medical record

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    9 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Baylor Scott and White Health

    RECRUITING

    Dallas, Texas, 75246, United States

  • HealthPartners

    RECRUITING

    Minneapolis, Minnesota, 55425, United States

  • Henry Ford Health Systems

    RECRUITING

    Detroit, Michigan, 48202, United States

  • Kaiser Permanente Colorado

    RECRUITING

    Denver, Colorado, 80247, United States

  • Kaiser Permanente Georgia

    RECRUITING

    Atlanta, Georgia, 30305, United States

  • Kaiser Permanente Hawaii

    RECRUITING

    Honolulu, Hawaii, 96814, United States

  • Kaiser Permanente Northwest

    RECRUITING

    Portland, Oregon, 97086, United States

  • Marshfield Clinic Health System

    RECRUITING

    Marshfield, Wisconsin, 54449, United States

  • Sanford Health

    RECRUITING

    Sioux Falls, South Dakota, 57117, United States

  • University of Chicago Medical Center

    ACTIVE_NOT_RECRUITING

    Chicago, Illinois, 60603, United States

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Other studies related to the condition(s) this trial covers.