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Which nerve block wins for hernia pain? a Head-to-Head test

NCT ID NCT06412406

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 03, 2026 · Last updated Aug 12, 2026 · Updated 3 times

Summary

This trial compares two ultrasound-guided nerve blocks—the external oblique intercostal plane block and the subcostal transversus abdominis plane block—for managing pain during and after paraumbilical hernia repair. Adults aged 18-65 scheduled for elective hernia surgery will receive one of the two blocks, and researchers will measure pain scores, heart rate, blood pressure, and the time until the first opioid request. The goal is to see which block provides better pain relief and potentially reduces opioid use.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
External oblique intercostal plane block or subcostal transversus abdominis plane block (nerve blocks)
What this could lead to
If one block proves better, it could become the preferred method for managing pain in hernia repair, reducing the need for opioids and speeding recovery.
What could go wrong
This is a small, early-stage comparison, so results may not apply to all patients. Nerve blocks carry risks like infection, bleeding, or nerve damage, though rare.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

62 people

The number who actually took part.

Started

Feb 2024

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age between 18 and 65 years with a body mass index (BMI) of 18-35 kg/m2 2. patients with the American Society of Anesthesiologists (ASA) physical status I/II 3. Patients scheduled for elective paraumbilical hernia Exclusion Criteria: * 1-Known hypersensitivity to the study drugs. 2-Body Mass Index \> 40 kg/m2. 3- Inability to accurately describe postoperative pain to investigators. 4-Opioid tolerance or dependence. 5-Preexisting history of chronic pain. 6-History of renal, liver, cardiac, neuropsychiatric disorder problems. 7-Bleeding or coagulation abnormality. 8-Patients who received any analgesic 24 h before surgery 9-Patients who have difficulty understanding the study protocol

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Medicine Assuit University

    Asyut, Egypt

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