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Neck injection showdown: which route eases arm pain best?

NCT ID NCT03389620

Symptom relief Sponsor: Duke University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two standard ways of giving steroid injections for nerve pain in the arm that comes from the neck. One method injects near the nerve root in the neck, the other in the back of the spine. Researchers measured pain relief in 74 adults to see if one route is safer or more effective.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dexamethasone (a corticosteroid)
What this could lead to
If this trial succeeds, it could show which injection method works better for arm nerve pain, helping doctors choose the safest and most effective option.
What could go wrong
This is a small, completed Phase 2 study with only 74 participants. Results may not apply to everyone, and the injections carry risks like infection or nerve damage, though rare.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

74 people

The number who actually took part.

Started

Jan 2018

Finished

Sep 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Unilateral cervicogenic upper extremity radiculopathy (with or without accompanying neck pain) * Baseline numerical pain scale (NRS) score \> 4 Exclusion Criteria: * Recent (i.e., \< 2 months) cervical spine surgery * Recent (i.e., \< 1 month) cervical epidural or upper extremity corticosteroid injection * Contraindication or inability to the undergo procedure * Inability to provide informed consent * Expected inability to complete follow-up assessment * Contraindication to receiving contrast material (precluding an epidurogram)

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cervicogenic upper extremity radiculopathy

Contacts and locations

Locations

  • Duke Radiology and Orthopaedic Clinic

    Durham, North Carolina, 27710, United States