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Laser vs. balloon: which works best for narrowed windpipe?

NCT ID NCT04719845

Disease control Sponsor: Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two procedures—laser resection and dilatation—for treating benign (non-cancerous) narrowing of the windpipe. The goal was to see which one better prevents the narrowing from coming back within two years. The trial was terminated early, so the results are limited.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Endoscopic laser resection or dilatation (procedures)
What this could lead to
If successful, this could show which procedure is better at preventing the airway from narrowing again after treatment.
What could go wrong
The trial was terminated early, so it may not provide clear answers. Both procedures have risks like scarring or recurrence, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

108 people

The number who actually took part.

Started

Mar 2021

Finished

Nov 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Benign simple tracheal stenosis (length of stenosis \<1cm without underlying cartilage damage) with planned endoscopic treatment (first treatment or recurrence) Exclusion Criteria: * Less than 18 years old * Pregnant * Incapacity to give informed consent * Underlying inflammatory suspected to be the cause of stenosis (ex : granulomatosis with polyangitis)

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Conditions

The condition(s) this trial relates to.

tracheal stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Tracheal stenosis

Contacts and locations

Locations

  • Centre Hospitalier Universitaire Grenoble Alpes

    Grenoble, France

  • Hôpital Larrey, University Hospital of Toulouse

    Toulouse, France

  • Hôpital Nord

    Marseille, France

  • Institut universitaire de cardiologie et de pneumologie de Québec (IUCPQ)

    Québec, Canada

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