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New lung injury measure tested in children with breathing failure

NCT ID NCT06586411

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 40 children with a severe lung condition called pediatric acute respiratory distress syndrome (pARDS). Researchers compared a new measurement called the Oxygen Stretch Index with the standard Oxygenation Index to see which better reflects lung damage. They also checked how these measures relate to other lung injury markers. The goal was to find a more accurate way to assess disease severity in these young patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

40 people

The number who actually took part.

Started

Nov 2024

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Intubated pARDS patients in PICU

Ages

1 month to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * pARDS patient * Intubated patient Exclusion Criteria: * Perinatal lung disease * Cardiac failure and fluid overload * Patients whose respiratory mechanics cannot be measured * Age under 1 month or above 18 years old * ETT leakage \> 18%

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Acibadem University, Acibadem Altunizade Hospital

    Istanbul, Turkey (Türkiye)

  • Aydin Obstetric and pediatrics Hospital

    Aydin, 09020, Turkey (Türkiye)

  • Cam Sakura Research and Training Hospital

    Istanbul, 34001, Turkey (Türkiye)

  • Erzurum Regional Research and Training Hospital

    Erzurum, 25180, Turkey (Türkiye)

  • Istanbul Aydin University

    Istanbul, Turkey (Türkiye)

  • The Health Sciences University Izmir Behçet Uz Child Health and Diseases Research and Training Hospital

    Izmir, 35200, Turkey (Türkiye)

  • The Health Sciences University Izmir Behçet Uz Child Health and Diseases Research and Training Hospital

    Izmir, Turkey (Türkiye)

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