New lung injury measure tested in children with breathing failure
NCT ID NCT06586411
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 40 children with a severe lung condition called pediatric acute respiratory distress syndrome (pARDS). Researchers compared a new measurement called the Oxygen Stretch Index with the standard Oxygenation Index to see which better reflects lung damage. They also checked how these measures relate to other lung injury markers. The goal was to find a more accurate way to assess disease severity in these young patients.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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40 people
The number who actually took part.
- Started
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Nov 2024
- Finished
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Oct 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Intubated pARDS patients in PICU
- Ages
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1 month to 18 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * pARDS patient * Intubated patient Exclusion Criteria: * Perinatal lung disease * Cardiac failure and fluid overload * Patients whose respiratory mechanics cannot be measured * Age under 1 month or above 18 years old * ETT leakage \> 18%
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Acibadem University, Acibadem Altunizade Hospital
Istanbul, Turkey (Türkiye)
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Aydin Obstetric and pediatrics Hospital
Aydin, 09020, Turkey (Türkiye)
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Cam Sakura Research and Training Hospital
Istanbul, 34001, Turkey (Türkiye)
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Erzurum Regional Research and Training Hospital
Erzurum, 25180, Turkey (Türkiye)
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Istanbul Aydin University
Istanbul, Turkey (Türkiye)
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The Health Sciences University Izmir Behçet Uz Child Health and Diseases Research and Training Hospital
Izmir, 35200, Turkey (Türkiye)
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The Health Sciences University Izmir Behçet Uz Child Health and Diseases Research and Training Hospital
Izmir, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.