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Cheap fluid may shield heart better during surgery

NCT ID NCT06414330

Disease control Sponsor: Assiut University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested two different solutions used to protect the heart during bypass surgery. One is a modified version of a common fluid (Ringer acetate), the other is a standard solution (HTK). Researchers checked which one led to fewer abnormal heart rhythms and less heart muscle damage after surgery. 124 adults having coronary bypass surgery took part.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ringer acetate based modified Del Nido cardioplegia solution
What this could lead to
If it works, this could show that a cheaper, widely available fluid protects the heart better during surgery, reducing complications.
What could go wrong
This is a small, completed trial with 124 patients, so results may not apply to all heart surgeries. The benefit over standard care may be small or absent.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

124 people

The number who actually took part.

Started

Jun 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. ≥ 18 years old 2. Any gender 3. Surgery demands cardiopulmonary bypass and cardioplegia. 4. CABG surgeries Exclusion Criteria: 1. \< 18 years old 2. Emergency surgeries 3. Off pump CABG surgeries 4. Taking cardioplegia other than Del Nido or HTK cardioplegia

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Conditions

The condition(s) this trial relates to.

coronary artery disorder myocardial ischemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiac ischemia

Contacts and locations

Locations

  • Assiut university, faculty of medicine, anesthesia and ICU and pain management department

    Asyut, Asyut Governorate, 71515, Egypt

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