Which test best predicts chemo risks in seniors? new study aims to find out
NCT ID NCT07163169
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at three simple tests—CARG, G8, and a frailty scale—to see which one best predicts chemotherapy side effects in cancer patients aged 65 and older. Researchers will assess 150 patients before they start chemo and track side effects during treatment. The goal is to find the most accurate tool to help doctors make safer treatment decisions for older adults.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors choose the best screening tool to predict chemotherapy side effects in older adults, leading to safer and more personalized cancer treatment.
- What could go wrong
- This is an observational study, not a treatment trial, so it won't directly improve outcomes. The results may not apply to all cancer types or chemotherapy regimens.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 150 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2024
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population will consist of adult oncology patients aged 65 years and older who are scheduled to receive systemic chemotherapy for solid tumors at the Çanakkale Onsekiz Mart University Medical Faculty, Department of Medical Oncology. Eligible participants must have a confirmed cancer diagnosis and a predefined chemotherapy regimen (adjuvant, neoadjuvant, or palliative), but must not have yet started treatment at the time of enrollment.
- Ages
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65 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged 65 years or older. * Histologically confirmed cancer diagnosis with a pre-planned chemotherapy regimen (adjuvant, neoadjuvant, or palliative intent). * Chemotherapy not yet initiated at the time of enrollment. * Clinically stable condition, as assessed by the oncologist. * Willingness and ability to provide written informed consent. Exclusion Criteria: * Presence of acute infection or advanced organ failure (cardiac, hepatic, or renal). * Severe psychiatric illness or cognitive impairment that interferes with the ability to complete assessments. * Patients receiving concurrent hormonal therapy, targeted therapy, immunotherapy, or radiotherapy. * Diagnosis of hematologic malignancies (e.g., leukemia, lymphoma, myeloma).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Çanakkale Onsekiz Mart Univercity
Çanakkale, 17020, Turkey (Türkiye)
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