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Which Add-On drug gives better pain relief for pelvic fracture surgery?

NCT ID NCT07485127

Symptom relief Sponsor: Sohag University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial compares two drugs—dexamethasone and dexmedetomidine—added to standard spinal anesthesia for pelvic fracture surgery. Sixty adults will be split into two groups to see which combination provides longer pain relief and better recovery. The goal is to find a safer, more effective way to manage pain during and after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dexamethasone and dexmedetomidine (as adjuvants to bupivacaine)
What this could lead to
If one drug works better, it could improve pain control and recovery for people undergoing pelvic fracture surgery.
What could go wrong
This is a very early, small study with only 60 participants, so results may not apply to everyone. The drugs may not show a clear difference or could have unexpected side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Early phase 1

The earliest testing in people: a first look at safety, in a very small group.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age from 20 to 80 years. * Both sexes. * Patients will be classified as American Society of Anesthesiologists (ASA) class I - II. * Patient scheduled for surgical fixation of pelvic fracture. Exclusion Criteria: * Patients with drug addiction, and sepsis. * Infection at the injection site. * Sensitivity to local anesthetics. * Coagulopathy. * Kidney failure, liver failure. * History of previous paresis in the operation area.

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Conditions

The condition(s) this trial relates to.

hip fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Fracture pelvis

Contacts and locations

Locations

  • Sohag University

    Sohag, 82511, Egypt