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Pig or cow? study tests which collagen dressing heals tooth holes best

NCT ID NCT05802602

Disease control Sponsor: University of Nebraska Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two collagen wound dressings—one from pigs and one from cows—placed in tooth extraction sites along with a bone graft. Nineteen non-smoking adults aged 19-65 who needed a premolar or front tooth pulled took part. Researchers measured soft tissue thickness and bone density changes to see which dressing worked better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
porcine collagen membrane and bovine collagen wound dressing
What this could lead to
If one dressing works better, it could improve healing and bone quality after tooth extraction and grafting.
What could go wrong
This is a small, completed study with only 19 participants, so results may not apply to everyone. The dressings are already available, so no major breakthrough is expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

19 people

The number who actually took part.

Started

Apr 2023

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

19 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Non-smoking * Aged 19-65 * Requiring premolar or anterior tooth extraction and graft procedures * Good general health * Willing to provide informed consent. Exclusion Criteria: * History of radiation therapy or bisphosphonate use * Pregnancy or breastfeeding * Systemic conditions that affect bone healing * Contraindications to dental implants * Inability to attend follow-up visits.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Wound heal

Contacts and locations

Locations

  • University of Nebraska Medical Center, College of Dentistry

    Lincoln, Nebraska, 68503, United States

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