New study aims to improve lung nodule diagnosis with advanced biopsy techniques
NCT ID NCT07326072
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two ways to take tissue samples from lung nodules that are hard to reach with a regular bronchoscope. About 228 adults aged 18 to 90 with suspicious lung nodules will be randomly assigned to get either an ultra-thin cryobiopsy or a forceps biopsy, both guided by electromagnetic navigation. The goal is to see which method is safer and better at diagnosing the nodules.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 228 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Sep 2025
- Expected to finish
-
Jul 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 90 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. age 18 to 90 years; 2. pulmonary nodules detected by chest CT, suspected malignant nodules or unknown cause should be confirmed by biopsy; 3. chest CT showed that the nodule was located in the segmental bronchus and below, and the maximum diameter of the nodule was 8 mm to 30 mm.It was not accessible by conventional bronchoscopy; 4. if chest CT showed multiple pulmonary nodules, one of the pulmonary nodules was selected as the target lesion. Exclusion Criteria: 1. contraindications to the bronchoscopy procedure; 2. high risk of bleeding, such as bronchial artery penetration or suspected lung metastasis of renal cell carcinoma; 3. electromagnetic source implanted in the body; 4. contraindications to anesthesia; 5. pregnant woman; 6. participated in other studies within three months and did not withdraw or finish, affect the observation of this study; 7. inability or unwillingness to provide informed consent or comply with the follow-up schedule.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Diagnosis are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Beijing Chaoyang Hospital
Beijing, Beijing Municipality, 100020, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can MRI replace surgery for staging bladder cancer?
- AI reads routine heart tests to predict artery blockages
- Can a glowing mouthwash spot oral cancer before biopsy?
- Artificial intelligence may detect Children's heart disease from a routine ECG
- Rural heart failure diagnosis gets a boost from Point-of-Care testing
- Dentist's eye goes digital: 3D scans may spot gum disease faster