New genetic test may predict colon cancer return
NCT ID NCT02110329
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether a genetic test called QMPSF can help predict if stage II or III colon cancer will come back after surgery. Researchers analyzed tumor tissue from 401 patients for specific DNA changes. The goal was to see if these genetic markers are linked to cancer recurrence and survival rates.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this genetic test could help doctors better predict which colon cancer patients are at higher risk of recurrence, guiding more personalized treatment decisions.
- What could go wrong
- This is an observational study, not a treatment trial. The test is still experimental and may not prove accurate enough for routine use. Results need validation in larger, diverse groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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401 people
The number who actually took part.
- Start date
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May 2010
- Finished
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Nov 2013
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * age over 18 * localized colon cancer * proven adenocarcinoma * surgery R0 * no metastatic disease * stage II or III * WHO performance status 0, 1 or 2 * availaible frozen tissue * written consent * no major co-morbidities Exclusion Criteria: * metastatic disease * hereditary colorectal cancer * rectal cancer
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Chu Dijon
Dijon, 21079, France
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Chu Hopitaux de Rouen
Rouen, 76031, France
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Chu Lille
Lille, 59037, France
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Other studies related to the condition(s) this trial covers.
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