Collagen pills tested for better scar healing
NCT ID NCT06787924
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether taking oral collagen supplements can increase collagen in the skin of people who had weight-loss or tummy-tuck surgery. 102 participants received either collagen peptides or a placebo for several weeks. Researchers then compared skin biopsies and scar quality to see if the supplement made a difference.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bovine collagen peptides
- What this could lead to
- If it works, this could point toward a simple supplement to improve skin healing and scar quality after surgery.
- What could go wrong
- This is a small, completed trial with no phase designation, so results may not be conclusive. Collagen supplements are not regulated like drugs and may not work for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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102 people
The number who actually took part.
- Started
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Apr 2025
- Finished
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Dec 2025
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged 18-75 years after metabolic bariatric surgery. * Patients will be randomly selected from the hospital's electronic patient system. Exclusion Criteria: * 1\. Allergies or Sensitivities: * Patients with known allergies or hypersensitivity to collagen or any components of the collagen supplements (e.g., bovine, marine sources). 2\. Chronic Skin Conditions: * Participants with skin disorders that could influence collagen production or degradation (e.g., psoriasis, eczema, scleroderma) should be excluded as these conditions might interfere with the study's outcomes. 3\. Autoimmune or Connective Tissue Diseases: * Patients with autoimmune diseases (e.g., lupus, rheumatoid arthritis) or connective tissue disorders (e.g., Ehlers-Danlos syndrome) might exhibit abnormal collagen metabolism and could confound the study's results. 4\. Use of Collagen or Nutritional Supplements: * Participants currently taking collagen supplements or other nutritional supplements (e.g., vitamin C, glucosamine, chondroitin) that could affect collagen synthesis or turnover should be excluded. A washout period may be required for those who have recently used such supplements. 5\. Hormonal Treatments or Medications: * Patients on treatments that could affect collagen metabolism (e.g., corticosteroids, hormone replacement therapy, anabolic steroids) should be excluded, as these could alter the body's collagen production or degradation. 6\. Pregnancy or Lactation: * Pregnant or breastfeeding women should be excluded due to the physiological changes during pregnancy and lactation that could affect collagen metabolism. 7\. Major Surgeries or Trauma: * Recent major surgeries or significant trauma within the last 6-12 months, especially those involving connective tissue repair, as these could alter collagen levels independently of supplementation. 8\. Smoking: * Smokers or individuals who have recently quit smoking, as smoking is known to reduce collagen synthesis and impair skin healing. 9\. Chronic Illnesses: * Patients with chronic illnesses such as diabetes, liver disease, or kidney disease, which could impair collagen metabolism or affect skin health. 10\. Uncontrolled Metabolic Disorders: * Participants with uncontrolled metabolic disorders (e.g., severe obesity, untreated hyperlipidemia) may have altered collagen metabolism and should be excluded unless specifically studied. 11\. Participation in Other Clinical Trials: * Patients currently enrolled in other clinical trials involving supplements, medications, or procedures that could interfere with the study outcomes should be excluded.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Facility Name: The surgical department of Medical Research Institute Hospital, Alexandria University, Alexandria, Facility
Alexandria, Egypt
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Other studies related to the condition(s) this trial covers.
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