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Brain training tailored to deficits may curb relapse and crime

NCT ID NCT06981351

Disease control Sponsor: The Mind Research Network Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 17, 2026 · Last updated Aug 18, 2026 · Updated 1 time

Summary

This trial tests whether matching cognitive training to a person's specific thinking deficits can improve real-world outcomes for incarcerated individuals with substance use disorders. Participants are assigned to one of two types of training—one targeting attention to context, the other targeting emotional control—either matched or mismatched to their deficit profile. The study uses brain scans and behavioral tasks to see if the right match reduces substance use, improves adjustment, and lowers the chance of reoffending after release.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Two types of cognitive remediation training: Attention to Context (ATC) training and Affective Cognitive Control (ACC) training
What this could lead to
If matching training to a person's specific cognitive deficit works, it could lead to more effective rehabilitation programs that reduce substance use and reoffending after prison.
What could go wrong
This is an early-stage trial, and the training may not produce lasting real-world improvements. The effects could be small or not generalize beyond the study setting.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 288 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2025

Expected to finish

May 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Currently incarcerated * No uncorrectable auditory or visual deficits * Able to speak and/or understand English * 5th grade reading level or higher * IQ score = 80 or above * Lifetime history of substance use disorder based on DSM criteria * No history of dementia or other cognitive disability * No indication of current psychotic disorder * No major medical illness or CNS disease * Scores from the Psychopathy Checklist-Revised (PCL-R) meet criteria for one of the designated treatment groups Exclusion Criteria: \-

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Conditions

The condition(s) this trial relates to.

antisocial personality disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Antisocial behavior

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Mind Research Network/Lovelace Biomedical Research Institute

    RECRUITING

    Albuquerque, New Mexico, 87106, United States

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