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Morning espresso may Kick-Start digestion after pancreatic surgery

NCT ID NCT04205058

Symptom relief Sponsor: Azienda Ospedaliera Universitaria Integrata Verona Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial investigates whether drinking coffee after pancreatic surgery can help the bowel start working again sooner. About 200 adults who had open pancreatic surgery will receive either regular coffee, decaf coffee, or water twice a day. The main goal is to see how quickly they have their first bowel movement, with the hope that coffee may speed recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
caffeine
What this could lead to
If it works, this could offer a simple, low-cost way to speed up bowel recovery after pancreatic surgery.
What could go wrong
This is a single-center trial with 204 participants, so results may not apply to all patients. Coffee may not speed recovery more than water.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

204 people

The number who actually took part.

Started

Jan 2020

Finished

Jan 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Elective open pancreaticoduodenectomy * Age ≥ 18 years * American Society Anesthesiologists (ASA) score ≤ 3 * Ability of the subject to understand aims and clinical consequences of the trial * Written informed consent Exclusion Criteria: * American Society Anesthesiologists (ASA) score ≥ 4 * Need for early postoperative Intensive Care Unit care * Need for naso-gastric tube on postoperative day one * Intolerance to coffee * Refuse to assume coffee * Pregnancy * Surgical procedures performed different from pancreaticoduodenectomy * Impaired mental status or language problems

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Conditions

The condition(s) this trial relates to.

bowel dysfunction intestinal disorder pancreas disorder paralytic ileus Postoperative Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bowel dysfunction Pancreatic diseases Postoperative complications Postoperative ileus

Contacts and locations

Locations

  • AOUI Verona

    Verona, 37124, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.