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New drug targets Hard-to-Treat lung cancer in early trial

NCT ID NCT04189614

First seen Apr 03, 2026 · Last updated May 22, 2026 · Updated 7 times

Summary

This early-stage study tests an experimental drug called cofetuzumab pelidotin in 65 adults with a specific type of recurrent non-small cell lung cancer (NSCLC) that has a protein called PTK7. The drug is designed to deliver a toxin directly to cancer cells. The main goal is to see if it can shrink tumors, while also monitoring safety and survival. Participants must have already tried standard treatments like chemotherapy and immunotherapy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Asan Medical Center /ID# 222280

    Seoul, Seoul Teugbyeolsi, 05505, South Korea

  • CHA Bundang Medical Center /ID# 232514

    Seongnam, Gyeonggido, 13496, South Korea

  • Duplicate_Stanford University School of Med /ID# 213450

    Stanford, California, 94305-2200, United States

  • Highlands Oncology Group, PA /ID# 215383

    Springdale, Arkansas, 72762, United States

  • Hospital Universitario Fundacion Jimenez Diaz /ID# 215110

    Madrid, 28040, Spain

  • Hospital Universitario HM Sanchinarro /ID# 215102

    Madrid, 28050, Spain

  • Hospital Universitario Vall de Hebron /ID# 215729

    Barcelona, 08035, Spain

  • Linkou Chang Gung Memorial Hospital /ID# 222603

    Taoyuan City, 333, Taiwan

  • Moffitt Cancer Center /ID# 215101

    Tampa, Florida, 33612-9416, United States

  • National Cancer Center Hospital /ID# 218536

    Chuo-ku, Tokyo, 104-0045, Japan

  • National Cancer Center Hospital East /ID# 218537

    Kashiwa-shi, Chiba, 277-8577, Japan

  • National Cheng Kung University Hospital /ID# 222602

    Tainan, 704, Taiwan

  • Oncology Consultants /ID# 215932

    Houston, Texas, 77030-3306, United States

  • Rabin Medical Center. /ID# 217537

    Petah Tikva, 4941492, Israel

  • Rambam Health Care Campus /ID# 217536

    Haifa, 3109601, Israel

  • Samsung Medical Center /ID# 222906

    Seoul, Seoul Teugbyeolsi, 06351, South Korea

  • Sylvester Comprehensive Cancer Center /ID# 216433

    Miami, Florida, 33136-1002, United States

  • Tennessee Oncology, PLLC /ID# 215326

    Nashville, Tennessee, 37203, United States

  • The Chaim Sheba Medical Center /ID# 217538

    Ramat Gan, Tel Aviv, 5265601, Israel

  • The Ohio State University /ID# 211088

    Columbus, Ohio, 43210, United States

  • Univ of Colorado Cancer Center /ID# 215295

    Aurora, Colorado, 80045, United States

  • University of Alabama at Birmingham - Main /ID# 213605

    Birmingham, Alabama, 35233, United States

  • University of Texas MD Anderson Cancer Center /ID# 215876

    Houston, Texas, 77030, United States

  • Virginia Cancer Specialists - Fairfax /ID# 216427

    Fairfax, Virginia, 22031, United States

  • Washington University-School of Medicine /ID# 213453

    St Louis, Missouri, 63110, United States

  • Yonsei University Health System Severance Hospital /ID# 222281

    Seoul, 03722, South Korea

Conditions

Explore the condition pages connected to this study.