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Special coating on brain stent may reduce dangerous narrowing

NCT ID NCT07420179

First seen Feb 19, 2026 · Last updated Jun 22, 2026 · Updated 11 times

Summary

This study tested whether a coated stent (Derivo 2 heal) causes less narrowing inside the artery than an uncoated stent after treating brain aneurysms. 21 adults with unruptured aneurysms in the internal carotid artery were randomly assigned to receive one of the two stents. Researchers measured narrowing on follow-up scans at 3 and 9 months to see if the coating helps keep the artery open.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Saarland University Hospital

    Homburg, Saarland, 66421, Germany

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Coated flow diverter stent (Derivo 2 heal)

What this could lead to

If the coated stent reduces narrowing, it could improve long-term outcomes for people with brain aneurysms treated with stents.

What could go wrong

This is a very small study (21 people) and only looks at a specific type of aneurysm. Results may not apply to all patients or show clear benefits.

Conditions

The condition(s) this trial relates to.

Aneurysm brain aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.