New study aims to find best CMV prevention for kidney transplant patients
NCT ID NCT07430683
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at two different approaches to prevent cytomegalovirus (CMV) infection in people who have received a kidney transplant from a living donor. The participants are at intermediate risk for CMV and are given standard anti-rejection medication. The goal is to see which strategy—daily preventive medication or monitoring and treating only if the virus appears—works better to keep patients healthy. Results may help doctors choose the best prevention plan for similar patients.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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68 people
The number who actually took part.
- Started
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Mar 2024
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. -Age ≥18 years. 2. -First living-donor kidney transplant. 3. -Intermediate CMV risk (recipient seropositive \[R+\], donor positive or negative \[D+/D-\]). 4-Induction immunosuppression with basiliximab. 5.-Ability to provide written informed consent. Exclusion Criteria: 1. -Multi-organ transplant recipients (e.g., pancreas-kidney, liver-kidney). 2. -Deceased donor transplant recipients. 3. -Primary non-function of the graft. 4. -Hyperacute rejection. 5. -Death within the first month post-transplant. 6. -Early graft loss due to surgical complications.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Universidad de Guadalajara
Guadalajara, Jalisco, 44280, Mexico
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Banked t cells target four viruses at once in children after transplant
- Can we outsmart Drug-Resistant CMV in transplant patients?
- Can we map CMV's spread in daycares to shield future pregnancies?
- Can immune cells predict herpesvirus danger in transplant patients?
- Can specially grown immune cells from donors beat viruses that won't go away?
- Immune cell levels may predict who will develop severe CMV after transplant