New study tracks hidden virus threat in liver transplant patients
NCT ID NCT05958186
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 800 children and adults who received a liver transplant in China to learn how often they get infected with cytomegalovirus (CMV), a common virus that can cause serious problems after transplant. Researchers tracked patients for one year, checking for CMV infections, organ rejection, and survival. The goal was to better understand the risks and improve care for transplant recipients.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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800 people
The number who actually took part.
- Started
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Aug 2023
- Finished
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Aug 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The participates had received their first orthotopic liver transplantation within 10 days prior. And there are no gender restrictions. The number of participants are 800.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Have received their first orthotopic liver transplant (the transplanted liver may be deceased donor or live donor graft) within 10 days prior. * Children group: Age ≤18yeas; * Adults group: Age \>18yeas; * Willingness to participate in the study * Ability to understand information material * Written informed consent Exclusion Criteria: * Have known Human immunodeficiency virus (HIV) infection (based on testing performed during the transplant evaluation process). * Participation in another investigational agent trial * Be undergoing multi organ transplant or have undergone prior organ transplant. Have expected life expectancy of less than 72 hours.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Shanghai General Hospital
Shanghai, China