Study reveals hidden risks for virus after kidney transplant
NCT ID NCT07621835
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 236 kidney transplant patients to find out why some fail to develop immune protection against cytomegalovirus (CMV) in the first 45 days after surgery. Researchers reviewed medical records to compare patients who had a strong immune response with those who did not. The goal is to help doctors predict and manage CMV risk without needing advanced immune tests.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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236 people
The number who actually took part.
- Started
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Jan 2019
- Finished
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Apr 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
We will conduct a retrospective, observational, multicenter cohort study of CMV-seropositive (R⁺) kidney transplant recipients who did not receive ATG induction, between 1 January, 2019 and 30 April, 2025.
- Ages
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18 years and older
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age \>18 years * Kidney or pancreas-kidney transplant recipients with positive CMV serology * QF-CMV test performed on day 45 post-transplant (window period between day 30 and day 60 post-transplant) * CMV PCR testing performed at least every two weeks during the first three months post-transplant Exclusion Criteria: * HIV-infected patients * Multivisceral transplant recipients * Patients scheduled to receive universal prophylaxis despite having a reactive QF-CMV result * Patients who received ATG induction therapy * Less than 6 months of post-transplant follow-up
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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HOSPITAL Universitario REINA SOFIA
Córdoba, 14004, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can digital tools and training help more kidney patients get transplants?