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One-Patient trial aims to fix genetic glitch behind rare nerve disease

NCT ID NCT07223632

First seen Nov 03, 2025 · Last updated Apr 29, 2026 · Updated 26 times

Summary

This study tests a custom-made drug (VCA-894A) in a single person with a rare genetic nerve disease called CMT2S. The drug is designed to correct a specific genetic error and restore a missing protein. The main goals are to check if the treatment is safe and if it can improve muscle function.

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Contacts and locations

Locations

  • Vanda Investigational Site

    Madison, Wisconsin, 53792, United States

Conditions

Explore the condition pages connected to this study.