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New study to see if suctioning out blood clots beats standard care for deep vein thrombosis

NCT ID NCT07573618

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two treatments for acute deep vein thrombosis (DVT) in the leg. Half of the 104 participants will receive standard blood-thinning medication alone, while the other half will also undergo a procedure to suction out the clot, sometimes with balloon dilation or a stent. Researchers will follow patients for 24 months to see which group has fewer complications like clot recurrence, lung clots, or long-term leg damage.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
thrombus aspiration procedure
What this could lead to
If successful, this could offer a more effective way to treat deep vein thrombosis and reduce long-term complications like post-thrombotic syndrome.
What could go wrong
This is a relatively small trial (104 people) and has not started recruiting yet. The procedure carries risks like bleeding or vessel damage, and it may not prove better than standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 104 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

Apr 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18-80, gender unrestricted; * Diagnosed as acute or subacute proximal deep venous thrombosis of the lower extremities through lower extremity venous ultrasound or enhanced CT of the lower extremity veins, with involvement of at least the common iliac vein, external iliac vein, or common femoral vein; * The subjects met the criteria for standard anticoagulation therapy combined with thrombus aspiration along with standard anticoagulation therapy; * The patient fully understands and voluntarily signs a written informed consent form; * Willing and able to comply with all the visit, treatment, and assessment procedures specified in the study protocol. Exclusion Criteria: * Bilateral deep iliofemoral vein thrombosis; * Femoral edema or femoral white swelling; * Inferior vena cava thrombosis; * History of deep vein thrombosis with a diagnosis of moderate to severe post-thrombotic syndrome; * The affected limb has previously had a venous stent implanted; * There are anatomical abnormalities affecting the intervention pathway, such as hypoplasia or dysplasia of the inferior vena cava, or other malformations of the iliac or inferior vena cava; * Presence of active major bleeding or clinically significant bleeding risk (hemoglobin \<80g/L or platelet count \<50×109/L); * Severe coagulation dysfunction, with an international normalized ratio \>1.7; * Uncontrolled severe hypertension (systolic blood pressure \>180 mmHg or diastolic blood pressure \>105 mmHg after medication); * Severe renal impairment, with a glomerular filtration rate \<30 mL/min/1.73m²; * Any interventional treatment for the target deep vein thrombosis within 30 days prior to enrollment; * Female patients in pregnancy or lactation; * Known history of allergies to drugs used during the study (such as contrast agents, anticoagulants, etc.); * Active malignant tumor; * In the judgment of the researchers, there are any other comorbidities, conditions, or poor adherence that may affect the study evaluation or place the patient at high risk.

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Conditions

The condition(s) this trial relates to.

post-thrombotic syndrome Postthrombotic Syndrome Venous Thrombosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

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  2. A doctor treating you

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