New study to see if suctioning out blood clots beats standard care for deep vein thrombosis
NCT ID NCT07573618
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two treatments for acute deep vein thrombosis (DVT) in the leg. Half of the 104 participants will receive standard blood-thinning medication alone, while the other half will also undergo a procedure to suction out the clot, sometimes with balloon dilation or a stent. Researchers will follow patients for 24 months to see which group has fewer complications like clot recurrence, lung clots, or long-term leg damage.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- thrombus aspiration procedure
- What this could lead to
- If successful, this could offer a more effective way to treat deep vein thrombosis and reduce long-term complications like post-thrombotic syndrome.
- What could go wrong
- This is a relatively small trial (104 people) and has not started recruiting yet. The procedure carries risks like bleeding or vessel damage, and it may not prove better than standard care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 104 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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Apr 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18-80, gender unrestricted; * Diagnosed as acute or subacute proximal deep venous thrombosis of the lower extremities through lower extremity venous ultrasound or enhanced CT of the lower extremity veins, with involvement of at least the common iliac vein, external iliac vein, or common femoral vein; * The subjects met the criteria for standard anticoagulation therapy combined with thrombus aspiration along with standard anticoagulation therapy; * The patient fully understands and voluntarily signs a written informed consent form; * Willing and able to comply with all the visit, treatment, and assessment procedures specified in the study protocol. Exclusion Criteria: * Bilateral deep iliofemoral vein thrombosis; * Femoral edema or femoral white swelling; * Inferior vena cava thrombosis; * History of deep vein thrombosis with a diagnosis of moderate to severe post-thrombotic syndrome; * The affected limb has previously had a venous stent implanted; * There are anatomical abnormalities affecting the intervention pathway, such as hypoplasia or dysplasia of the inferior vena cava, or other malformations of the iliac or inferior vena cava; * Presence of active major bleeding or clinically significant bleeding risk (hemoglobin \<80g/L or platelet count \<50×109/L); * Severe coagulation dysfunction, with an international normalized ratio \>1.7; * Uncontrolled severe hypertension (systolic blood pressure \>180 mmHg or diastolic blood pressure \>105 mmHg after medication); * Severe renal impairment, with a glomerular filtration rate \<30 mL/min/1.73m²; * Any interventional treatment for the target deep vein thrombosis within 30 days prior to enrollment; * Female patients in pregnancy or lactation; * Known history of allergies to drugs used during the study (such as contrast agents, anticoagulants, etc.); * Active malignant tumor; * In the judgment of the researchers, there are any other comorbidities, conditions, or poor adherence that may affect the study evaluation or place the patient at high risk.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
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The official record
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A doctor treating you
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