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Braces without wires: which aligner system expands your smile best?

NCT ID NCT07608302

Knowledge-focused Sponsor: University of Salamanca Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two popular clear aligner systems—Invisalign and Angel Aligner—to see how accurately they widen the upper jaw in adults with a narrow palate. Researchers measured the planned versus actual tooth movement in 60 participants using digital models. The goal is to help orthodontists choose the most predictable system for expanding the dental arch.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
clear aligner systems (Invisalign, Angel Aligner, Angel Aligner Pro)
What this could lead to
If successful, this study could help orthodontists choose the most predictable aligner system for widening the upper jaw, improving treatment outcomes for patients with a narrow palate.
What could go wrong
This is a completed study with only 60 participants, so results may not apply to everyone. The study measures dental movement, not long-term stability or patient satisfaction.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Feb 2024

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 43 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients with a full permanent dentition * Absence of auxiliary orthodontic appliances * A clinical indication for transverse expansion in both dental arches * Complete diagnostic and treatment records * Treatment plans involving a minimum of 15 aligners before any refinement phase * Confirmed adequate compliance with aligner wear (20-22 hours per day) * patients with skeletal Class I or mild skeletal Class II or III relationships (ANB angle ranging from 0° to 4° Exclusion Criteria: * Severe dental crowding (tooth size-arch length discrepancy exceeding -5 mm) * Active periodontal pathology * Treatment plans involving dental extractions

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Narrow palate

Contacts and locations

Locations

  • University of Salamanca

    Salamanca, Salamanca, 37008, Spain