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Which clear aligner design feels better? new study aims to find out

NCT ID NCT07660809

Symptom relief Sponsor: George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 21, 2026 · Updated 3 times

Summary

This study compares two common clear aligner trimming-line designs to see which one feels more comfortable to wear. Seventy orthodontic patients who already wear one design on their upper teeth and the other on their lower teeth will rate their comfort after at least four weeks. The goal is to help dentists choose the design that causes less discomfort.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
clear aligner trimming-line design (device)
What this could lead to
If one design is found to be more comfortable, it could help orthodontists choose better-fitting aligners for patients.
What could go wrong
This is a small, early observational study (70 people) that only measures comfort, not treatment success. Results may not apply to all patients or aligner brands.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

70 people

The number who actually took part.

Started

Jul 2026

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adolescent and adult patients (aged 15 years or older) in active orthodontic treatment with clear aligners, including finishing (refinement) aligners, in whom a supragingival trimming-line design is worn on one dental arch and a juxtagingival design on the contralateral arch. Eligible participants have worn the two designs for at least four weeks at the time the questionnaire is completed. Recruitment is conducted at a single orthodontic practice.

Ages

15 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adolescent or adult patient (aged 15 years or older) * Active orthodontic treatment with clear aligners, including finishing (refinement) aligners * Wearing two clear aligners with different trimming-line designs, one per dental arch: a supragingival design on one arch and a juxtagingival design on the contralateral arch * At least 4 weeks of wear of the two designs at the time of questionnaire completion * Good treatment compliance * Willing and able to complete the online questionnaire and provide the required consent Exclusion Criteria: * Mixed orthodontic treatment (aligners combined with fixed appliances) * Pre-existing neurological, cognitive, or speech disorders * Systemic conditions affecting the oral cavity (e.g., xerostomia, mucosal disorders)

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Conditions

The condition(s) this trial relates to.

Malocclusion

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Malocclusion Oral health Patient comfort

Contacts and locations

Locations

  • Aorys Clinic

    Sibiu, Sibiu County, 550027, Romania

More trials for these conditions

Other studies related to the condition(s) this trial covers.