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Major trial aims to stop kidney failure in its tracks

NCT ID NCT06058585

Disease control Sponsor: The George Institute Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is for adults with chronic kidney disease (CKD) who are already receiving standard care. It tests different treatments, alone or in combination, to see which best slows kidney decline and prevents kidney failure. About 1,000 participants will be followed for over two years.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 1,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2024

Expected to finish

Mar 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age ≥ 18 years 2. Known chronic kidney disease from any cause (eGFR ≥25 mL/min/1.73m2) 3. Currently receiving standard of care treatment according to treating physician 4. Eligible for randomisation in at least one recruiting domain-specific appendix 5. Participant and treating physician are willing and able to perform trial procedures Exclusion Criteria: 1. Planned to commence kidney replacement therapy or kidney transplant surgery in next 6 months 2. Life expectancy less than 6 months

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic kidney diseases

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    43 sites in 5 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • 201 Great King Street, Central Dunedin, Dunedin 9016, New Zealand

    RECRUITING

    Dunedin, 9016, New Zealand

  • Aotearoa Clinical Trials Trust, Middlemore Hospital

    RECRUITING

    Auckland, 2025, New Zealand

  • Apollo Hospitals

    RECRUITING

    Hyderabad, Telangana, India

  • Auckland City Hospital

    RECRUITING

    Auckland, 1023, New Zealand

  • Austin Health

    RECRUITING

    Heidelberg, Victoria, 3084, Australia

  • CARE-CHL Hospital

    RECRUITING

    Indore, Madhya Pradesh, India

  • Charak Hospital and Research Centre

    RECRUITING

    Lucknow, Uttar Pradesh, 226003, India

  • Colombo North Teaching Hospital

    RECRUITING

    Ragama, 11010, Sri Lanka

  • DKS Super Speciality Hospital, Raipur

    RECRUITING

    Raipur, Chhattisgarh, 492002, India

  • Dr Moopen's Medical College

    RECRUITING

    Meppādi, Kerala, 673511, India

  • Father Muller Medical College Hospital

    RECRUITING

    Mangaluru, Karnataka, 575002, India

  • Fortis Hospital

    RECRUITING

    Kolkata, West Bengal, 700107, India

  • GCS Medical College, Hospital & Research Centre

    RECRUITING

    Ahmedabad, Gujarat, 380025, India

  • Gitam Institute of Medical Sciences and Research

    RECRUITING

    Visakhapatnam, Andhra Pradesh, 530045, India

  • Gold Coast Hospital and Health Service

    RECRUITING

    Southport, Queensland, 4215, Australia

  • Health New Zealand, Te Whatu Ora Te Matau a Maui, Hawke's Bay Hospital

    RECRUITING

    Hastings, Hawkes Bay, 4120, New Zealand

  • Health New Zealand, Te Whatu Ora Waitemata, North Shore Hospital

    RECRUITING

    Auckland, 0620, New Zealand

  • Hospital Clinico Universitario València (INCLIVA)

    RECRUITING

    Valencia, Espana, 46010, Spain

  • John Hunter Hospital

    RECRUITING

    New Lambton Heights, New South Wales, 2305, Australia

  • Kandy National Hospital

    RECRUITING

    Kandy, 20000, Sri Lanka

  • Kurunegala Teaching Hospital

    RECRUITING

    Kurunegala, Sri Lanka

  • Lyell McEwin Hospital

    RECRUITING

    Elizabeth Vale, South Australia, 5112, Australia

  • Max Superspeciality Hospital, Dehradun

    RECRUITING

    Dehradun, 248001, India

  • Medway Hospital

    RECRUITING

    Chennai, Tamil Nadu, 600024, India

  • Mysore Medical College

    RECRUITING

    Dehradun, Dehradun, 248001, India

  • National Hospital of Sri Lanka

    RECRUITING

    Colombo, 00700, Sri Lanka

  • National Nephrology Specialized Hospital

    RECRUITING

    Colombo, Polonnaruwa, 51000, Sri Lanka

  • Nepean Blue Mountains Local Health District

    RECRUITING

    Kingswood, New South Wales, 2747, Australia

  • North Bengal Medical College & Hospital

    RECRUITING

    Siliguri, West Bengal, 734012, India

  • Patna Medical College and Hospital

    RECRUITING

    Patna, Bihar, 800001, India

  • Peradeniya Teaching Hospital

    RECRUITING

    Peradeniya, 20400, Sri Lanka

  • Private Bag 9742 Maunu Road, Horahora, Whangārei 0148, New Zealand

    RECRUITING

    Whangarei, 0148, New Zealand

  • Royal Adelaide

    RECRUITING

    Adelaide, South Australia, 5000, Australia

  • Shri Guru Ram Rai Medical College and Shri Mahant Indiresh Hospital

    RECRUITING

    Dehradun, Uttarakhand, 248001, India

  • South Metropolitan Health Service, Fiona Stanley Hospital

    RECRUITING

    Murdoch, Western Australia, 6150, Australia

  • Sri Jayewardenepura General Hospital

    RECRUITING

    Nugegoda, 10250, Sri Lanka

  • St George Hospital

    RECRUITING

    Kogarah, New South Wales, 2217, Australia

  • Sunshine Coast Hospital and Health Service

    RECRUITING

    Birtinya, Queensland, 4575, Australia

  • The Canberra Hospital

    RECRUITING

    Garran, Australian Capital Territory, 2605, Australia

  • Townsville University Hospital

    RECRUITING

    Douglas, Queensland, 4814, Australia

  • West Moreton Hospital & Health Service

    RECRUITING

    Ipswich, Queensland, 4305, Australia

  • Westmead Hospital

    RECRUITING

    Westmead, New South Wales, 2145, Australia

  • Yashoda Hospital Hitec City

    RECRUITING

    Hyderabad, Telangana, 500084, India

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