Can a spice and a mindset shift ease diabetic nerve pain?
NCT ID NCT07757399
First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time
Summary
This trial is testing whether taking a daily Ceylon cinnamon supplement, combined with a structured educational program, can improve blood sugar control, cholesterol levels, and nerve pain in adults with type 2 diabetes and painful diabetic peripheral neuropathy. About 900 participants will be randomly assigned to one of three groups: standard care, cinnamon alone, or cinnamon plus the educational program, for six months. The goal is to see if this combined approach offers better metabolic and pain relief than standard care alone.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Ceylon cinnamon supplement (1,000 mg/day) and a self-efficacy-based educational program
- What this could lead to
- If effective, this combination could offer a natural, low-cost way to improve blood sugar control and reduce painful nerve damage in people with type 2 diabetes.
- What could go wrong
- This is an early-stage trial, and results may not be conclusive. Cinnamon may interact with diabetes medications, and the educational program's impact may vary widely among participants.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 900 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosed with Type 2 Diabetes Mellitus (T2DM) for at least 6 months. * Confirmed diagnosis of painful diabetic peripheral neuropathy (PDPN). * Age between 18 and 65 years. * Able to provide written informed consent and willing to comply with the study protocol, supplement intake, and educational sessions. Exclusion Criteria: * Type 1 diabetes mellitus or gestational diabetes. * Severe renal or hepatic impairment. * Known allergy, hypersensitivity, or contraindication to cinnamon or related botanical products. * Pregnancy or lactation. * Concurrent participation in another clinical trial or severe psychiatric/cognitive disorders that hinder study participation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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