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Stress before infection may predict long COVID, study finds

NCT ID NCT05652634

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at whether chronic stress before catching COVID-19 makes long COVID more likely. Researchers followed 380 adults who tested positive for SARS-CoV-2 and had symptoms. They measured stress levels and tracked whether symptoms lasted beyond four weeks. The goal is to understand if stress is a risk factor, which could help identify people who might benefit from extra support.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If chronic stress is confirmed as a risk factor, it could point toward stress-management strategies to help prevent long COVID.
What could go wrong
This is an observational study, not a treatment trial. It cannot prove cause and effect, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

380 people

The number who actually took part.

Started

Feb 2023

Finished

Jun 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

After having been tested positive for SARS-CoV-2 and having received the invitation to participate in this study by the local health authority of the City of Graz, or the health authority of the Province of Styria, persons interested can visit the study website and sign in for getting contacted by the study team.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults (\>18 years); qPCR-test positive for SARS-CoV-2 infection; symptom(s) of acute COVID-19; inclusion within defined timeframe of one week after testing; data collection online, by phone and at study visits feasible Exclusion Criteria: * Insufficient knowledge of German language; lengths of hair at rear vertex less than 2 cm; pregnancy or postpartum less than 3 months; refusal to give informed consent

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Conditions

The condition(s) this trial relates to.

COVID-19 long COVID-19 Psychological Well-Being

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Medical University Graz, Division of Medical Psychology, Psychosomatics and Psychotherapy

    Graz, Styria, 8036, Austria

More trials for these conditions

Other studies related to the condition(s) this trial covers.