Stress before infection may predict long COVID, study finds
NCT ID NCT05652634
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looked at whether chronic stress before catching COVID-19 makes long COVID more likely. Researchers followed 380 adults who tested positive for SARS-CoV-2 and had symptoms. They measured stress levels and tracked whether symptoms lasted beyond four weeks. The goal is to understand if stress is a risk factor, which could help identify people who might benefit from extra support.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If chronic stress is confirmed as a risk factor, it could point toward stress-management strategies to help prevent long COVID.
- What could go wrong
- This is an observational study, not a treatment trial. It cannot prove cause and effect, and results may not apply to everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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380 people
The number who actually took part.
- Started
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Feb 2023
- Finished
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Jun 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
After having been tested positive for SARS-CoV-2 and having received the invitation to participate in this study by the local health authority of the City of Graz, or the health authority of the Province of Styria, persons interested can visit the study website and sign in for getting contacted by the study team.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults (\>18 years); qPCR-test positive for SARS-CoV-2 infection; symptom(s) of acute COVID-19; inclusion within defined timeframe of one week after testing; data collection online, by phone and at study visits feasible Exclusion Criteria: * Insufficient knowledge of German language; lengths of hair at rear vertex less than 2 cm; pregnancy or postpartum less than 3 months; refusal to give informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Medical University Graz, Division of Medical Psychology, Psychosomatics and Psychotherapy
Graz, Styria, 8036, Austria
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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