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New study aims to uncover Alzheimer's clues in down syndrome

NCT ID NCT05231798

First seen May 31, 2026 · Last updated Jun 15, 2026 · Updated 4 times

Summary

This study looks at how certain brain cells (cholinergic neurons) change with age in adults with Down syndrome, and how that relates to Alzheimer's disease risk. Researchers will use brain scans and EEGs to measure these changes in 30 adults aged 18-55 who do not have dementia. The goal is to better understand who might benefit from future treatments, but no treatment is given in this study.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Vanderbilt University Medical Center Clinical Research Center

    RECRUITING

    Nashville, Tennessee, 37212, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

Alzheimer Disease Down syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.