Can a daily antiseptic bath keep central lines safer for sick kids?
NCT ID NCT05995080
First seen Sep 16, 2026 · Last updated Sep 17, 2026 · Updated 1 time
Summary
Critically ill children with central venous catheters face a risk of bloodstream infections that can lead to longer hospital stays and serious complications. Researchers are testing whether bathing these children daily with a 2% chlorhexidine gluconate solution prevents central line-associated bloodstream infections better than standard soap and water bathing. The trial enrolls children aged 2 months to 18 years who have a temporary central line and are expected to stay in intensive care for at least 48 hours. It compares infection rates and catheter colonization between the two bathing methods.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- daily bathing with 2% chlorhexidine gluconate solution
- What this could lead to
- If it works, this could give pediatric intensive care units a simple bathing routine to reduce dangerous bloodstream infections in children with central lines.
- What could go wrong
- The trial is small and single-center, so results may not apply to other hospitals or patient groups. Chlorhexidine can irritate skin or cause allergic reactions in some children.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
247 people
The number who actually took part.
- Started
-
May 2023
- Finished
-
May 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
2 months to 18 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients between the ages of 2 months and 18 years who had a temporary central venous catheter * Patients whose follow-up is continued for at least 48 hours with a central venous catheter Exclusion Criteria: * Patients younger than 2 months of age * Patients with a intensive care unit stay shorter than 48 hours * Immunosuppressive patients * Patients with a history of allergic reaction to chlorhexidine * Patients with skin lesions that interfere with skin cleansing with chlorhexidine * Patients whose family did not give consent
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Bloodstream infection due to central venous catheter are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
IMU
Istanbul, Kadıköy, 34800, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.