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Engineered immune cells target abdominal cancer spread in early trial

NCT ID NCT07411599

First seen Feb 19, 2026 · Last updated Apr 30, 2026 · Updated 9 times

Summary

This study tests a new treatment for colorectal cancer that has spread to the lining of the abdomen. The treatment uses specially designed natural killer (NK) cells that target a protein called TROP2 on cancer cells and have a gene removed to help them work better. These cells are given both through a vein and directly into the abdomen, along with another drug called cetuximab. The main goal is to find the safest dose and check for side effects in about 28 adults.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.