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Ancient herbal mix tested for stubborn eczema in small trial

NCT ID NCT04686955

Disease control Sponsor: Taipei Veterans General Hospital, Taiwan Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed Phase 3 trial tested a Chinese herbal formula called Xiao-Xian-Gui-Fu-Tang in 19 people aged 6 to 30 with moderate to severe atopic dermatitis (eczema). Participants took the herbal blend or a placebo for several weeks. Researchers measured changes in eczema severity and quality of life. The study aims to see if adding traditional Chinese medicine can help control this chronic skin condition.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Xiao-Xian-Gui-Fu-Tang (a blend of Chinese herbs including Xiao-Feng-San, Dang-Gui-Yin-Zi, Bai-Xian-Pi, and Di-Fu-Zi)
What this could lead to
If effective, this herbal formula could offer an additional treatment option for people with moderate to severe atopic dermatitis, potentially reducing symptoms and improving quality of life.
What could go wrong
This is a very small Phase 3 trial with only 19 participants, so results may not apply to a broader population. The study is completed but no results are posted yet, and the herbal mixture may cause side effects or interact with other medications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

19 people

The number who actually took part.

Started

Jan 2021

Finished

Dec 2022

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

6 to 30 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 6 years old to 30 years old. * Diagnosis as an atopic dermatitis patient. * The score of the SCORAD is over 25. (moderate to severe atopic dermatitis) Exclusion Criteria: * Secondary bacterial infections * Received oral or intravenous steroid treatment, anti-biotics, phototherapy, or other immunosuppressive therapies in the previous 2 months. * Received Chinese herbal medicine treatment or acupuncture. * Pregnant woman or current breastfeeding. * Who had catastrophes illness now or in the past must be avoided. * Can not sign informed consent or can not communicate with the researcher. * Abnormal liver enzymes. * Abnormal kidney function tests (1.5 times higher than the upper normal limit)

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Conditions

The condition(s) this trial relates to.

atopic eczema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atopic dermatitis

Contacts and locations

Locations

  • Center for Traditional Medicine, Taipei VGH

    Taipei, 11217, Taiwan

  • Taipei Veterans General Hospital

    Taipei, Taiwan

More trials for these conditions

Other studies related to the condition(s) this trial covers.