Ancient herbs meet modern medicine in moyamoya trial
NCT ID NCT07286110
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding a traditional Chinese herbal formula (Qiqi Shengmai) to standard care can improve blood flow in the brains of people with moyamoya disease. About 66 adults aged 18 to 80 will receive either the herbal formula or a placebo for a set period. The goal is to see if the herbs help reduce the risk of stroke and improve brain function.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1
The first testing in people. Mainly checks safety and dose, usually in a small group.
- Participants
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About 66 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Imaging findings meeting the Western medical diagnostic criteria for moyamoya vasculopathy 2. Age between 18 and 80 years 3. The patient and family members are fully informed and voluntarily consent to participation, with the informed consent process conducted in accordance with GCP requirements 4. Willingness to receive Traditional Chinese Medicine treatment 5. Traditional Chinese Medicine syndrome differentiation consistent with liver-yang hyperactivity Exclusion Criteria: 1. Acute cerebrovascular events within the preceding 6 weeks 2. Known allergy to contrast agents or to the investigational medication 3. Presence of severe primary diseases involving the cardiac, pulmonary, hepatic, renal, endocrine, or hematopoietic systems 4. Pregnant or breastfeeding women 5. Patients scheduled to undergo cerebral revascularization surgery 6. Participation in other ongoing clinical trial
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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180 Fenglin Road, Xuhui District, Shanghai 200032,China
Shanghai, Shanghai Municipality, 200032, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Predicting the unpredictable: new model aims to forecast brain bleeds in moyamoya
- Can a daily pill and a simple physical therapy delay moyamoya strokes?
- Metaverse meets microsurgery: XR platform aims to sharpen brain bypass precision
- French biobank aims to unlock secrets of rare brain vessel diseases
- Your digital twin could help prevent another stroke
- Could a simple MRI and blood test predict moyamoya before it strikes?