New hope for kids with devastating rare cancers
NCT ID NCT05407441
Summary
This study is testing a combination of three drugs—tazemetostat, nivolumab, and ipilimumab—as a potential treatment for children and young adults with rare, aggressive cancers caused by missing specific proteins (INI1 or SMARCA4). The first part aims to find the safest dose, and the second part will see if the combination can effectively control these difficult-to-treat tumors. About 49 participants, aged 6 months to 21 years, will receive treatment for up to 2 years.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Boston Children's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Texas Children's Hospital
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Conditions
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