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Chewing gum may be the surprising new tool to recover smell and taste

NCT ID NCT07498062

Symptom relief Sponsor: University of Nottingham Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tested whether chewing flavored gum twice a day for 12 weeks could help people recover their sense of smell and taste. Thirty adults with smell or taste loss were split into three groups: one chewed flavored gum, one smelled liquid flavors, and one waited. The study aimed to see if this approach is practical and worth testing in a larger trial.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
chewing gum with flavor
What this could lead to
If it works, this could offer a simple, at-home method to help people regain their sense of smell and taste after loss.
What could go wrong
This is a very small pilot study with only 30 people. It is designed to test feasibility, not effectiveness, so results may not lead to a proven treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Oct 2024

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * • Aged between 18 and 65 years male and female * Have impairment in smell and/or taste (with a medical diagnosis or self-perception of between 3 months and 2 years) * Were able to smell and taste normally prior to the impairment (we anticipate that participants will have experienced the condition following a viral infection or idiopathically, etc) * Voluntary participation in the study * Willing to travel to Nottingham for 2 lab visits * Able to give informed written consent * Having not taken part in olfactory training or related research in the last 3 months or any study providing an inconvenience allowance. Exclusion Criteria: * • Physical damage in oral and/or nasal cavity due to surgery, trauma, etc. * Active infection with a virus that impedes smell and/or taste perception, sinonasal diseases, Parkinson's disease * Chewing or biting difficulty that would restrict chewing gum regularly * Allergy to chewing gum ingredients * Pregnancy or lactating * Having taken part in a research study in the last 3 months involving invasive procedures or an inconvenience allowance (this must remain for ALL UoN FMHS UREC approved studies)

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Conditions

The condition(s) this trial relates to.

Ageusia anosmia Dysgeusia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ageusia Anosmia Dysgeusia Parosmia Phantosmia

Contacts and locations

Locations

  • University of Nottingham

    Loughborough, Leicestershire, LE12 5RD, United Kingdom

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