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C-Section scar may impact IVF outcomes, new study investigates

NCT ID NCT04869007

Knowledge-focused Sponsor: University Hospital, Angers Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a defect in the uterine scar from a previous C-section (called an isthmocele) can lower the chance of getting pregnant with assisted reproduction like IVF. Researchers will measure the scar using a special ultrasound in 250 women before their IVF procedure. The goal is to see if women with a significant scar defect have lower pregnancy rates.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If it works, this could clarify whether a cesarean scar defect reduces the chance of pregnancy with IVF, guiding future treatment decisions.
What could go wrong
This is an observational study, not a treatment trial. It cannot prove cause and effect, and results may not apply to all women.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 250 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2022

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients referred to an ART procedure for secundary infertility with a history of at least one cesarean section (single or multi-scarred uterus).

Ages

18 to 43 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria : * Patients with a history of at least one cesarean section (single or multi-scarred uterus). * Age between 18 and 43 years old * Secondary infertility requiring ART techniques (FIV or FIV ICSI). * A Hysterosonography examination as part of the pre-ART assessment allowing for the detection of the presence of an isthmocele. * French speaking patients * Patient affiliated to or beneficiary of a social security scheme Non-inclusion criteria : \- Refusal to participate in the study.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cesarean section; dehiscence

Contacts and locations

Locations

  • Creteil University Hospital

    Créteil, France

  • Hospital Center Sud Francilien

    Corbeil-Essonnes, France

  • Tenon Hospital Paris

    Paris, France

  • UH Angers

    Angers, 49933, France

  • University Hospital of Rennes

    Rennes, France

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