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Zapping stress: device shows promise for calming soldiers

NCT ID NCT06034496

Symptom relief Sponsor: Tufts University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether a device that sends a mild electrical current through the head (cranial electrotherapy stimulation, or CES) can reduce stress in soldiers. 76 soldiers used the device or a fake version daily for 20 sessions over 4-6 weeks. Researchers measured heart rate, stress hormones, anxiety, and decision-making during a stressful shooting task. The goal was to see if CES helps the body and mind stay calmer under pressure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Cranial electrotherapy stimulation (CES) device (Alpha-Stim)
What this could lead to
If it works, this could point toward a drug-free way to help people manage acute stress and anxiety.
What could go wrong
This is a small, early-stage study in soldiers, so results may not apply to the general public. The sham group also received a device, so the real benefit of the electrical current may be small.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

76 people

The number who actually took part.

Started

Sep 2023

Finished

Nov 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18-40 years of age (17-40 if emancipated minor) * Can sit and stand freely. * Have not used or experienced CES administration in the past. * Agree to have their data stored in a repository (database) for future use. Exclusion Criteria: * Use of prescription medications, other than oral contraceptives * Women only: 1. Pregnant or plan to become pregnant during the study 2. Nursing * History of: 1. A neurological or psychological disorder (such as depression, anxiety disorders, migraines, cluster headaches, seizures, Post-traumatic stress disorder (PTSD) or panic attacks). 2. Cardiac disease (including arrhythmia or fast or skipped heart beats). 3. Implanted medical devices, such as pacemakers. 4. Hypertension. 5. Insomnia 6. Head injury (including neurosurgery, concussion, TBI, skull fracture, hematoma) 7. Illness that caused brain injury 8. Any other brain-related condition (such as traumatic brain injury) 9. Metal in the head (outside of mouth, such as shrapnel, surgical clips, or fragments from welding or metalwork) 10. Implanted medical device (e.g., pacemaker, insulin pump)

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Conditions

The condition(s) this trial relates to.

anxiety disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anxiety state

Contacts and locations

Locations

  • Tufts University

    Medford, Massachusetts, 02155, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.