Nerve block may offer quick relief for breathless ICU patients
NCT ID NCT07182695
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether a nerve block in the neck (cervical erector spinae plane block) can reduce the feeling of shortness of breath in ICU patients with acute respiratory failure. Thirty participants will receive the block, and their breathing distress will be measured using patient-reported scales and observer ratings over 24 hours. The goal is to see if this simple procedure can provide rapid relief without heavy sedation.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- cervical erector spinae plane block (a nerve block using local anesthetic)
- What this could lead to
- If it works, this could point toward a new way to quickly relieve severe shortness of breath in ICU patients without heavy sedation.
- What could go wrong
- This is a very small, early study with only 30 people and no comparison group. The block may not work for everyone, and there are risks like infection or allergic reaction.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2025
An estimate. Start dates often move.
- Expected to finish
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Mar 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Consecutive adult patients in the mixed medical-surgical ICU of a tertiary university hospital (Hacettepe University Hospital, Ankara, Türkiye). The ICU manages acute respiratory failure due to pneumonia, COPD/asthma, pulmonary edema, and post-operative causes. Patients who receive a cervical ESP block for dyspnea as are observed for changes over 24 hours.
- Ages
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18 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * ICU admission with acute respiratory failure. * Patient or legally authorized representative provides consent. * Cervical ESP block performed for dyspnea treatment Exclusion Criteria: * Infection at block site. * Known diaphragm paralysis. * Known allergy to local anesthetics. * Refusal of consent (patient or representative).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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