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New drug cocktail targets Hard-to-Treat cancers in early trial

NCT ID NCT02321501

First seen Nov 10, 2025 · Last updated Jun 18, 2026 · Updated 32 times

Summary

This early-phase study tests a combination of two drugs, ceritinib and everolimus, in people with advanced solid tumors or a specific type of lung cancer (ALK-positive NSCLC) that has stopped responding to standard treatments. The main goal is to find the safest dose and see if the combo can shrink tumors or slow their growth. About 37 participants will take part, and researchers will also monitor side effects and how long the benefit lasts.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

The condition(s) this trial relates to.

cancer metastatic malignant neoplasm Neoplasm Metastasis non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.