Can less dye give clear brain images?
NCT ID NCT07302646
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether using less contrast dye during brain scans for unruptured aneurysms can still produce clear images. About 244 adults will be randomly assigned to receive either the standard dye amount or a reduced amount. The goal is to find a safer, more comfortable way to perform these scans without losing image quality.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 244 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Adult participant at the time of consent (age between 18 and 80 years old); Scheduled diagnostic cerebral angiography as part of routine care: * Initial assessment of the IA (suspected or detected in non-invasive imaging); * Follow-up of one or more IAs (treated or untreated); * Conscious and oriented participant, able to undergo the procedure under simple local anaesthesia; * Participant able to understand the objectives of the research and provide a dated, signed informed consent form; * Participant able to answer oral or written questions (French-speaking or understanding French); * For women of childbearing potential: negative serum β-HCG test at the inclusion visit; * Participant covered by a social security health insurance plan. Exclusion Criteria: * Emergency cerebral angiography; * Participants with other neurovascular conditions (AVM, AVF, etc.) in addition to an IA; * Participants with any contraindication to the use of ICM; * Pregnancy or breastfeeding; * Participants whose physical or psychological condition requires sedation or general anaesthesia for the procedure; * Participants with communication or cognitive disorders; Incapable participants (subject to legal protection measures: curatorship, guardianship, judicial protection, future protection mandate, family authorization).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Imagerie Interventionnelle Vasculaire Hôpitaux Universitaires de Strasbourg 1, place de l'Hôpital, 67 091 STRASBOURG Cedex
Strasbourg, France
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