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New immunotherapy drug shows promise for advanced skin cancer

NCT ID NCT06981325

First seen Jan 12, 2026 · Last updated Jun 23, 2026 · Updated 26 times

Summary

This phase 2 trial is testing the drug cemiplimab as a first treatment for people with advanced basal cell carcinoma, a type of skin cancer. The study will enroll 34 adults who have not received prior treatment with hedgehog inhibitors. Researchers want to see if cemiplimab can shrink tumors and control the cancer over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Helios Klinikum Erfurt

    RECRUITING

    Erfurt, Germany

  • Helios Klinikum Oberhausen

    RECRUITING

    Oberhausen, Germany

  • Johannes Wesling Klinikum

    RECRUITING

    Minden, Germany

  • Nationales Centrum für Tumorerkrankungen (NCT)

    RECRUITING

    Heidelberg, Germany

  • Universitätsklinikum Erlangen

    RECRUITING

    Erlangen, Germany

  • Universitätsklinikum Leipzig

    RECRUITING

    Leipzig, Germany

  • Universitätsklinikum Tübingen

    RECRUITING

    Tübingen, Germany

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cemiplimab (a cancer immunotherapy drug)

What this could lead to

If successful, this could offer a new first-line treatment option for advanced basal cell carcinoma, helping shrink tumors and control the disease without needing prior therapy.

What could go wrong

This is a small, early-phase trial with only 34 participants, so results may not apply to everyone. The drug can cause immune-related side effects, and it may not work for all patients.

Conditions

The condition(s) this trial relates to.

basal cell carcinoma skin basal cell carcinoma skin neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.